Neuroprotective Natural Products

Clinical Aspects and Mode of Action

Goutam Brahmachari

• Editorial: Wiley-VCH
• Año: 2017
• ISBN:
  9783527803804
• Edición: 1
• Categoría: Medicina
• Categoría: Farmacología

Focusing on the molecular mechanisms of powerful naturally occurring agents and their implication for drug discovery, this timely book presents an overview of the most recent research advances in the field of bioactive natural products and natural drug formulations to combat today's destructive diseases.
To this extent, the authors discuss the most severe neurological disorders in our modern civilization, such as Alzheimer's, Parkinson's and Huntington's disease, as well as ischemic brain stroke and depression. The emerging diversity of active compounds is covered in detail, including flavonoids, cannabinoids and oleanolic acid, while experts in the field explain the chemistry, mode of action and clinical aspects of novel neuroprotective natural products. In each case, the benefits of treatments using natural products are addressed from the perspective of modern as well as traditional medicine.
With its multidisciplinary viewpoint, this is the ideal companion for medicinal and natural products chemists as well as neuroscientists, biochemists, pharmacologists, neurobiologists, and phytotherapists.

Índice

• Cover
• Title Page
• Copyright
• Table of Contents
• List of Contributors
• Dedication
• Preface
• Editor Biography
• Chapter 1: Neuroprotective Natural Products: Clinical Aspects and Modes of Action – An Overview
• Chapter 2: Neuroprotective Agents: An Overview on the General Modes of Action
• Chapter 3: Beneficial Upshots of Naturally Occurring Antioxidant Compounds against Neurological Disorders
• Chapter 4: Natural Neuroprotectives for the Management of Parkinson's Disease
• Chapter 5: Neuroprotective Effect of Ayurvedic Preparations and Natural Products on Parkinson’s Disease
• Chapter 6: Lipid Peroxidation and Mitochondrial Dysfunction in Alzheimer’s and Parkinson’s Diseases: Role of Natural Products as Cytoprotective Agents
• Chapter 7: Marine-Derived Anti-Alzheimer’s Agents of Promise
• Chapter 8: Natural Products against Huntington’s Disease (HD): Implications of Neurotoxic Animal Models and Transgenics in Preclinical Studies
• Chapter 9: Possible Role of Neuroprotectants and Natural Products in Epilepsy: Clinical Aspects and Mode of Action
• Chapter 10: Neuroprotective Effects of Flavonoids in Epilepsy
• Chapter 11: The Role of Noncompetitive Antagonists of the N-Methyl- d-aspartate (NMDA) Receptors in Treatment-Resistant Depression
• Chapter 12: Safety and Efficacy of Ashwagandha (Withania somnifera)
• Chapter 13: Cannabinoids: A Group of Promising Neuroprotective Agents
• Index
• End User License Agreement